The Air Ambulance was called to a collision yesterday involving a school bus and a car with a Nicholson couple on board at Wiseleigh.

A 73 year old man is in a critical condition while a 69 year old woman is in a stable condition - both flown to hospitals in Melbourne.

40 children and a number of adults were assessed at the scene on the Great Alpine Road by paramedics but didn’t require treatment or transport.

Elsewhere in Gippsland, a motorcyclist was killed after colliding with a four wheel drive at Drouin.

A man behind the wheel of the Landcruiser stopped at the scene and is assisting police.